Cellulose Ethers

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Cellulose Ethers

Hypromellose(HPMC)
Hydroxypropyl Methylcellulose (HPMC), also known as Hypromellose, is a cellulose derivative where hydroxyl groups on the cellulose backbone are chemically modified with hydroxypropyl and methyl groups. This modification makes it soluble in cold water and gives it good film-forming, thickening, and emulsifying properties.

Pharmaceuticals Industry

  • Used as a controlled-release agent in tablets and capsules
  • A binder and coating agent for oral dosage forms
  • In eye drops and artificial tears as a lubricant and to retain moisture

Detergent Industry

HPMC is used to increase the viscosity of liquid detergents and cleaning products, giving them a better texture and making them easier to handle and apply.

Construction Industry

HPMC is used as a thickening agent and water-retaining agent in dry mortar. It ensures that the mortar has sufficient moisture for hydration reactions, thereby ensuring the strength of the mortar.

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Key facts about Hypromellose

  • Uses:

    • In eye drops and artificial tears as a lubricant to relieve dry eyes.
    • As a film-forming agent in oral tablets and capsules to control drug release.
    • In ophthalmic solutions as a thickening agent to improve viscosity.
    • In food as a stabilizer, emulsifier, and thickener.
    • In cosmetics for its moisture retention and film-forming properties.

  • Properties:

    • Water-soluble and forms a clear, viscous solution.
    • Non-toxic, non-irritant, and generally considered safe.
    • Stable across a wide range of pH and temperature conditions.
Common Uses of HPMC

  1. Pharmaceuticals:

    • Used as a controlled-release agent in tablets and capsules
    • A binder and coating agent for oral dosage forms
    • In eye drops and artificial tears as a lubricant and to retain moisture

  2. Food Industry:

    • Acts as a thickener, stabilizer, and emulsifier in baked goods, sauces, and dressings
    • Used as a vegetarian alternative to gelatin

  3. Cosmetics and Personal Care:

    • Used in creams, lotions, and shampoos for thickening and stabilizing formulations

  4. Industrial Applications:

    • Used in construction materials as a water retention agent
    • Employed in adhesives and paints
Safety

HPMC is generally regarded as safe (GRAS) by regulatory agencies. It is non-toxic and non-irritating in typical uses.

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